WebJan 1, 2001 · Growth plate chondrocyte proliferation, hypertrophy, and extracellular matrix secretion lead to the formation of new cartilage, chondrogenesis ( 13 ). Simultaneously, the growth plate is invaded from the metaphysis by blood vessels and bone cell precursors, which remodel the cartilage into bone tissue ( 14 ). WebThe fetal growth plate is primarily composed of three distinct types of chondrocyte types: round, flat, and hypertrophic chondrocytes ( Fig. 1.2 ). The majority of chondrocytes …
IJMS Free Full-Text Whole-Transcriptome Sequencing of Antler …
WebSep 29, 2024 · Confocal microscopic images of rabbit chondrocyte proliferation study staining (a,aʹ) with mitotracker assay kit with scaffold, (b,bʹ) with mitotracker assay kit immersed in SGNR, and (c,cʹ ... WebWith OA onset, chondrocytes undergo multiple changes, in terms of proliferation, viability, but also secretory profile. The acquisition of a hypertrophic phenotype (producing aberrant type X collagen and catabolic MMP-13 protease) by chondrocytes is well documented and contributes to OA development. figure roof angle
PDGF regulates chondrocyte proliferation through activation of …
WebApr 13, 2024 · AMA Style. Yao H, Jiang R, Chen D, Li Y, Song M, Sun Z, Long G, Wu L, Hu W. Whole-Transcriptome Sequencing of Antler Tissue Reveals That circRNA2829 Regulates Chondrocyte Proliferation and Differentiation via the miR-4286-R+1/FOXO4 Axis. WebApr 13, 2024 · The results of cell counting kit-8 (CCK-8) and 5-ethynyl-2′-deoxyuridine (EdU) experiments demonstrated that the overexpression of circRNA2829 significantly promoted chondrocyte proliferation, while the downregulation of circRNA2829 inhibited the proliferation of chondrocytes ( Figure 6 A–C). WebDec 6, 2016 · Although the inactivation of P53 and RB is involved in the pathogenesis of osteosarcomas, the deletion of p53 and inactivation of Rb are insufficient to enhance chondrocyte proliferation, indicating the presence of multiple inhibitory mechanisms against sarcomagenesis in chondrocytes. grocery benefits for those on medicare