site stats

Chondrocyte specific marker

WebJan 15, 2024 · SDF-1α, the most common isoform of stromal cell-derived factor 1, has shown vital effects in regulating chondrocyte proliferation, maturation, and chondrogenesis. Autophagy is a highly conserved biological process to help chondrocytes survive in harsh environments. However, the effect of SDF-1α on chondrocyte autophagy is still … WebBased on cluster-specific regulatory networks, protein activity was inferred for scRNA-seq data by a final metaVIPER algorithm run. ... WSB1, JMJD6, TSPYL2, HMGB2) and chondrocyte senescence marker proteins (SOX9, COL10A1). This may be partly caused by the insufficient sequencing depth and high dropout rate of scRNA-seq. Furthermore, a …

Gene expression profiling of chondrogenic differentiation …

WebApr 6, 2024 · Chondrogenic transcription factor SOX9 and cartilage matrix specific markers ACAN and COL2A1 were expressed in chondrocytes (Figure 1C). 5 We identified EC1/2 by expression of feature genes including CDH5, CD34 and PECAM1, pericytes by ACTA2, MYH11 and TAGLN (Figure 1C). 25-29 FAP, FBLN1 and COL1A2 were specifically … WebChondrocytes are the only type of cells found in cartilage. Chondrocytes have different morphologies due to their different locations in cartilage. Juvenile chondrocytes are … gartlwasserfall https://etudelegalenoel.com

A high-resolution route map reveals distinct stages of chondrocyte ...

WebJan 30, 2007 · Flow cytometry analysis showed that CD44, CD151, and CD49c were expressed at significantly higher levels in chondrocytes with higher chondrogenic … WebChondrocytes, which differentiate following the condensation of mesenchymal stem cells, are responsible for the secretion of extracellular matrix molecules, such as collagens and proteoglycans. Transcription factor SOX9 is critical for … WebHigh-density cultures are widely used as an in vitro model for studies of embryonic cartilage formation. In the present study we investigated the suitability of high-density cultures for the redifferentiation of dedifferentiated chondrocytes. When primary human chondrocytes were cultured in alginate beads, some cells emigrated into Petri dishes. gartlove country kennels

Chondrocyte Specific Markers - Primary Antibodies

Category:Life Free Full-Text Soluble and EV-Associated Diagnostic and ...

Tags:Chondrocyte specific marker

Chondrocyte specific marker

Expression of chondrocyte markers by cells of normal and …

WebChondrocyte Specific MarkersClear Sorting & Filtering Show Filter Hide Filter; Catalogue Number Description Target / Localization Key Applications Species Reactivity; AB1031: Anti-Aggrecan Antibody Initiation of chondrogenesis Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting Web166 Cellular and Molecular Characteristics of Chondrocytes Derived from Patients with Osteoarthritis Reveal Their Applicability in Matrix-Assisted Autologous Chondrocyte Transplantation

Chondrocyte specific marker

Did you know?

WebJan 30, 2007 · We identified markers that allow characterization of the capacity of monolayer-expanded chondrocytes to form in vitro cartilaginous tissue and enable enrichment for subpopulations with higher chondrogenic capacity. These markers might be used as a means to predict and possibly improve the outcome of cell-based cartilage … WebSep 1, 2003 · The alpha1 (X) collagen gene (Col10a1) is the only known hypertrophic chondrocyte-specific molecular marker. Until recently, few transcriptional factors specifying its tissue-specific expression have been identified.

WebFeb 21, 2024 · Chondrocytes, which make up the majority of the cells in all samples, are further split into three empirically defined populations: cartilage progenitor cells (CPCs), fibrochondrocyte progenitors (FCPs), and homeostatic chondrocytes (HomCs), as well as four new populations known as C1–4 ( Figures 1D,F ). WebApr 27, 2024 · Characterized chondrocyte implantation (CCI) was developed to optimize ACI outcomes, necessitating a precise chondrocyte phenotype evaluation before implantation. 29, 30, 31 Therefore, the...

WebAug 4, 2014 · Sox9controls chondrocyte proliferation and their progression into hypertrophy (6). Collagen X is the most specific marker of hypertrophic chondrocytes (HCs), the Col10a1gene being expressed only in prehypertrophic and hypertrophic chondrocytes in the growth plate (7). WebDec 15, 2024 · In females, 91 miRNAs were downregulated and 53 miRNAs were upregulated. The data showed gender-specific differences in miRNA content in OA EVs . EV-associated lncRNA KLF3 AS1 from MSCs affects chondrocyte proliferation and inhibition of chondrocyte apoptosis through the miR-206/GIT1 pathway .

WebFeb 17, 2024 · Several markers, including Mgp, Nt5e, Mmp13, Ibsp, Col3a1, and Sp7 were also up-regulated or ectopically activated in subsets of mutant ACCs. Importantly, the …

WebNational Center for Biotechnology Information black shorts nylonWebSep 1, 2000 · As model chondrocyte marker gene we have used the gene for mouse type II collagen (Col2a1) which is expressed in all chondroprogenitor cells and at high levels … black shorts on amazonWeb1 hour ago · Baronas et al. paired human height GWASs with functional genome-wide screening of growth-plate chondrocytes. Targets were enriched in height heritability and genes critical for endochondral ossification. This study emphasizes that functional assays in relevant tissues can refine likely causal genes from GWASs and implicates new … gartloch road glasgowWebOct 16, 2016 · All of those are the markers of chondrocyte differentiation. After that stage is chondrocyte prehypertrophy, which is marked by parathyroid hormone 1 receptor (Pth1r) and Indian hedgehog (Ihh) expression. Then, the stage goes into early hypertrophic chondrocytes that express collagen, type X, α 1 (Col10a1). black shorts no pocketsWebNational Center for Biotechnology Information black shorts nikeWebApr 14, 2024 · NKX3.2 was identified as being specifically expressed in cartilage tissues, and it delayed chondrocyte differentiation. miRNA-326 regulated chondrocyte differentiation by targeting NKX3.2. black short snow bootsWebChondrocyte phenotype was characterized through the cell membrane-associated extracellular matrix antigens. EDTA, used to obtain single cells from monolayer cultures, did not affect the cell-associated matrix. gartly aberdeen scotland