Guf1 gene and link with disease
WebGUF1 PATHOLOGY CANCER ANTIBODIES AND VALIDATION Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in renal cancer (favorable) and … WebMar 4, 2015 · GTPase of unknown function 1 (Guf1) is a mitochondrial protein in eukaryotes. Although this protein was identified several years ago, its physiological role in mammals remains elusive. Here, we...
Guf1 gene and link with disease
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WebLocated in mitochondrion. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 40. Orthologous to human GUF1 (GTP binding elongation factor GUF1). [provided by Alliance of Genome Resources, Apr 2024] Guf1 GUF1 homolog, GTPase [ (house mouse)] Gene ID: 231279, updated on 14-Mar-2024. Summary. … WebGUF1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.
WebThe following gRNA sequences were designed by Feng Zhang’s laboratory at the Broad institute* to uniquely target the GUF1 gene within the human genome. These gRNA sequences are for use with WT SpCas9, or as crRNA for use with WT SpCas9 protein, to introduce a DSB for genome editing. WebJun 20, 2008 · Guf1 Is Located in the Mitochondrial Matrix—While prokaryotic LepA and eukaryotic Guf1 proteins are highly conserved, the eukaryotic proteins consistently show N-terminal extensions that are absent in LepA proteins (Fig. 1B, Pre).These sequences show the characteristics of mitochondrial targeting signals. In a genome-wide screen a fusion …
WebGenetic disorders can be: Chromosomal: This type affects the structures that hold your genes/DNA within each cell (chromosomes). With these conditions, people are missing or have duplicated chromosome material. Complex (multifactorial): These disorders stem from a combination of gene mutations and other factors. WebIn 3 sibs, born of consanguineous Algerian parents, with developmental and epileptic encephalopathy-40 (DEE40; 617065 ), Alfaiz et al. (2016) identified a homozygous …
WebExpression of GUF1 (FLJ13220) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... GUF1: Gene description: GUF1 homolog, GTPase: Protein class i. Disease related genes: Predicted location i Intracellular: Number of transcripts i. 1: HUMAN PROTEIN ATLAS INFORMATION i. RNA category i ...
WebGUF1 (GTP binding elongation factor GUF1) HGNC: EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam: Mus musculus (house mouse): Guf1 (GUF1 homolog, GTPase) Transitive Ortholog Pipeline: Transitive Ortholog Pipeline: Rattus norvegicus (Norway rat): Guf1 (GTP binding elongation factor GUF1) Transitive Ortholog Pipeline: … christentum johannesWebMar 29, 2024 · GUF1, a gene encoding a novel evolutionarily conserved GTPase in budding yeast. Kiser GL, et al. Yeast, 1995 Oct. PMID 8553703 The proteomic reactor facilitates … christentum palästinaWeb19 hours ago · Credit: University of Hawaii at Manoa. A potential link between intestinal bacteria and the disproportionately higher rates of certain chronic disease and mental … christer jonsson advokatWebOct 5, 2024 · Nonalcoholic steatohepatitis (NASH) is an advanced stage of nonalcoholic fatty liver disease (NAFLD) with serious consequences that currently lacks approved pharmacological therapies. Recent studies suggest the close relationship between the pathogenesis of NAFLD and the dysregulation of RNA splicing machinery. christer jonsson hudiksvallWebHuman diseases caused by Guf1 mutations The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in … christer johansson riseWebNM_021927.3(GUF1):c.1360A>T (p.Ile454Phe) AND Inborn genetic diseases Clinical significance: Uncertain significance (Last evaluated: Oct 5, 2024) Review status: 1 star out of maximum of 4 stars christentum rom kaiserWebOct 5, 2024 · RT-PCR showed that the PA-induced AS of several mitochondrial function-related genes (Polg2, Nudt13, Guf1, Rnasel, and Nme4) was significantly reversed in … christer jonsson kalmar